An international team of researchers in Sweden and the United States of America succeeded in the process of planting a genetically modified benchrigon cell that is conducted on humans; To restore a patient with type 1 diabetes his ability to produce self -insulin.
The 42 -year -old who has diabetes has been infected since childhood, to plant island cells taken from a healthy donor, who was injected into a helped muscle, and within 12 weeks, the cells began to produce insulin in response to high blood sugar levels after meals, without the need for immunosuppressive medications.
This technique aims in the process used to overcome the main obstacle to cell transplantation, which is the rejection of the immune system, where three genetic adjustments were made using “CRISPR” technology, which included reducing the antigens recognized by T -cells, and enhancing the production of “CD47” protein that protects cells from fungal immunity.
