Walid Sabri
A consultant family medicine and diabetes, Dr. Faisal bin Jaafar Al -Mahrous, said that several recent scientific studies revealed a disturbing link between type 2 diabetes and an increase in the risk of multiple types of cancer, most notably the advanced breast cancer of the aspect of statistics that confirm clear increases in prostate cancers, liver, pancreas, lung, and colon, in addition to a noticeable rise in uterine cancers at Women, while a decrease in some tumors such as esophagus and gallbladder cancer was observed.
Dr. Faisal Al -Mahrous added, in a statement to “Al -Watan” that according to one of the studies, there is a possible explanation for this phenomenon, as the “xosums” found in the blood of diabetics re -programs immune cells inside the tumors, which makes it less able to face cancer and more resistant to treatments.
He continued that these results combined raising the alarm, and highlighting the necessity of periodic examination of diabetics, as well as adopting healthy lifestyles to reduce risk, while scientists continue to search for new mechanisms to understand the relationship and develop more effective treatment strategies.
Dr. Al -Mahrous pointed out that a wide Dutch study showed a strong relationship between type 2 diabetes and advanced breast cancer, explaining that women with diabetes are 28% more vulnerable to infection with aggressive tumors compared to non -injured, explaining that the study included 6267 women who were diagnosed with breast cancer between 2002 and 2014, including 1567 women who were diabetes of type II.
He indicated that the tumors in this category were more advanced and widespread in the lymph nodes surrounding the breast, which makes the treatment more difficult, while women who used insulin and the number of 388 of them at least for a period of more than 3.4 years, did not show a remarkable difference in the tumor properties, and the researchers did not find a direct relationship between the duration of the use of insulin and the aggression of cancer.
Dr. Al -Mahrous emphasized that previous research indicated that the increase in insulin levels may support the growth of tumors, but this study did not confirm this, suggesting that the reason is due to the small size of the sample used in analyzing the relationship with insulin, and therefore the researchers recommended to conduct larger studies to clarify the image.
A consultant family medicine and diabetes explained that doctors advise women with diabetes to undergo periodic examinations of the breast through X -rays, and inform the doctor as soon as any blocks or pain appears, especially since the diabetes itself may constitute a general risk factor for cancer.
Dr. Al -Mahrous added that a Chinese study is the largest so far to examine the relationship of diabetes with cancer, as it included 410,191 patients with type 2 diabetes without any cancer disease history, and they were followed from July 2013 to December 2017, and during this period, 8,485 new cancer cases were recorded.
He added that the results showed that the risk of cancer increased by 34% in men and 62% in women with diabetes compared to the general population.
He pointed out that men have emerged a significant increase in prostate cancer that reached 86%, and diabetes has been associated with an increase in the risk of several other cancers: leukemia, skin cancer, thyroid cancer, lymphoma, kidney cancer, liver cancer, pancreatic cancer, lung cancer, colon and rectal cancer, and stomach cancer. On the other hand, the results showed a clear decrease in the possibility of esophageal cancer among men with diabetes.
A consultant family medicine and diabetes explained that women have had the greatest risk of nasal pharynx cancer, as the percentage exceeded weakness compared to non -injured, and diabetes was associated with increasing the risk of cancer: liver, esophagus, thyroid gland, lung, pancreas, lymph nodes, uterus, colon and rectal, blood, cervix, breast, and stomach, while there was a decrease in the possibility of gallbladder cancer.
He indicated that this study, published in Journal of Diabetes, relied on a huge database collected by Shanghai’s public hospitals since 2013, and researchers assert that the results impose the need for special strategies for early examination of cancer in diabetics.
He added that a study conducted by Boston American University tried to understand the cause of type 2 diabetes patients, especially the resulting obesity, with more aggressive cancers, where the researchers found that external vesicles “xosums” found in the blood of people with diabetes change and directly affect the immune cells inside breast tumors.
Dr. Al -Mahrous added that these changes make immune cells weak, and thus allow tumors to grow and spread more easily, resulting in more aggressive and less response tumors.
He pointed out that the researchers relied on three -dimensional models of tumors taken from breast cancer patients (org on the patient) and solved them using the technique of mono -cell -cell DNA sequence, and this technique has shown that diabetes re -programs the immune environment for the tumor, which may explain the failure of some current treatments in this category.
He explained that the research published in Springer Nature emphasized that this is the first time that it has linked the external vesicles for diabetics and weak immunity within human breast tumors, stressing that this opens the door to develop new more specialized treatments for millions of patients around the world.
A consultant family and diabetes medicine indicated that on the other hand, scientists at the University of Limrick University in Ireland were able to discover a new human body called the Mensnery, and it was previously believed that it was merely a fold that links the intestine to the abdominal wall, but recent research has proven to be an independent member of its characteristics, and it was officially redefined in the book “Instantine”.
He added that the kisses had been described by Leonardo Da Vinci in 1508, but he remained neglected until the modern discovery, and today it is taught to medical students as a stand -alone member.
He indicated that the function of the alarm has not been determined yet, but researchers are likely to have an important role in colon and rectal cancer, bowel infections, obesity, and diabetes, stressing that scientists hope that this discovery will lead to a better understanding of the relationship of chronic diseases and perhaps developing new treatment methods.
Dr. Al -Mahrous concluded that women with type 2 diabetes are 28% more vulnerable to advanced breast cancer, and in China the risk of cancer increased by 34% for men and 62% for women with diabetes, and diabetes is linked to an increase in the risk of developing prostate, liver, pancreas, lung, breast, and colon. Enemy cancer and difficulty treating them. He added that the discovery of a “drunk” member may reveal new links between diabetes and cancer, stressing that the periodic examination and the modification of lifestyle remain the basic means of prevention.
