Monday 14/April/2025 – 07:06 AM
Detect study New, on the fact that the parasitic infection resulting from schistosomiasis, which is one of the diseases that are endemic to many developing countries, may stimulate genes associated with cancer in the cervical lining, which raises researchers’ concern about the possibility of the development of the disease even after treatment, according to what was published in the New York Post.
Genetic activity raises doubts after treatment
According to the research team, the genetic changes resulting from the infection did not stop after taking the treatment, but it was noted that these changes are more severe for some women after their recovery, which indicates the need to closely monitor their health condition even after the disappearance of the infection.
What is schistosomiasis?
Schoolsia is a parasitic disease caused by worms that live in freshwater, and spread widely in the areas, which suffer from a lack of sanitation and clean water services, such as parts of Africa and the Middle East, and the infection begins when the parasite larvae penetrate the skin while swimming or bathing in contaminated water.
Inside the body, these larvae grow to turn into extreme worms that put their eggs in the urinary and genital tract, which causes chronic infections that may lead to tissue damage and the emergence of cellular changes associated with an increase in the risk of cancer, especially bladder cancer .. As for its relationship to cervical cancer, it was unclear to this study.
The researchers analyzed samples of the cervical tissue of 39 women from Tanzania, including those who were afflicted with S. Haematobium’s parasites, and others were not injured, and the injured were treated with the drug “Brazicuantel”, which is known for its effectiveness against the adult worms, and samples were gathered before and after treatment for a period ranging between four and 12 months.
The study showed that there are nine genes that were acted differently in the injured compared to non -injured. After treatment, additional changes appeared in 23 genes in women who were sought, and 29 generations in the treatment of treatment compared to those who have never been injured.
“These molecular changes indicate a possibility of a relationship between the previous infection and an increase in cell capacity for cancerous transformation.
Merclan warned that some women who were seen showed greater signs of genetic activity associated with cancer than those who are still infected. It recommended that this category should be monitored after recovery, and the treatment not to be considered the end of the medical follow -up.
The study indicated that in addition to the use of Brazicuantel, it may be useful to think of supportive treatments such as anti -inflammatory or treatments that adjust the response of the immune system to reduce long -term damage.
