Home entertainment Bone marrow niches orchestrate stem-cell hierarchy and immune tolerance

Bone marrow niches orchestrate stem-cell hierarchy and immune tolerance

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  • Jones, D. L. & Wagers, A. J. No place like home: anatomy and function of the stem cell niche. Nat. Rev. Mol. Cell Biol. 9, 11–21 (2008).

    Article 
    PubMed 
    CAS 

    Google Scholar 

  • Comazzetto, S., Shen, B. & Morrison, S. J. Niches that regulate stem cells and hematopoiesis in adult bone marrow. Dev. Cell 56, 1848–1860 (2021).

    Article 
    PubMed 
    PubMed Central 
    CAS 

    Google Scholar 

  • Morrison, S. J. & Scadden, D. T. The bone marrow niche for haematopoietic stem cells. Nature 505, 327–334 (2014).

    Article 
    ADS 
    PubMed 
    PubMed Central 
    CAS 

    Google Scholar 

  • Kiel, M. J. et al. SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells. Cell 121, 1109–1121 (2005).

    Article 
    PubMed 
    CAS 

    Google Scholar 

  • Ding, L., Saunders, T. L., Enikolopov, G. & Morrison, S. J. Endothelial and perivascular cells maintain haematopoietic stem cells. Nature 481, 457–462 (2012).

    Article 
    ADS 
    PubMed 
    PubMed Central 
    CAS 

    Google Scholar 

  • Ding, L. & Morrison, S. J. Haematopoietic stem cells and early lymphoid progenitors occupy distinct bone marrow niches. Nature 495, 231–235 (2013).

    Article 
    ADS 
    PubMed 
    PubMed Central 
    CAS 

    Google Scholar 

  • Acar, M. et al. Deep imaging of bone marrow shows non-dividing stem cells are mainly perisinusoidal. Nature 526, 126–130 (2015).

    Article 
    ADS 
    PubMed 
    PubMed Central 
    CAS 

    Google Scholar 

  • Shen, B. et al. A mechanosensitive peri-arteriolar niche for osteogenesis and lymphopoiesis. Nature 591, 438–444 (2021).

    Article 
    ADS 
    PubMed 
    PubMed Central 
    CAS 

    Google Scholar 

  • Kusumbe, A. P. et al. Age-dependent modulation of vascular niches for haematopoietic stem cells. Nature 532, 380–384 (2016).

    Article 
    ADS 
    PubMed 
    PubMed Central 
    CAS 

    Google Scholar 

  • Kusumbe, A. P., Ramasamy, S. K. & Adams, R. H. Coupling of angiogenesis and osteogenesis by a specific vessel subtype in bone. Nature 507, 323–328 (2014).

    Article 
    ADS 
    PubMed 
    PubMed Central 
    CAS 

    Google Scholar 

  • Calvi, L. M. et al. Osteoblastic cells regulate the haematopoietic stem cell niche. Nature 425, 841–846 (2003).

    Article 
    ADS 
    PubMed 
    CAS 

    Google Scholar 

  • Zhang, J. et al. Identification of the haematopoietic stem cell niche and control of the niche size. Nature 425, 836–841 (2003).

    Article 
    ADS 
    PubMed 
    CAS 

    Google Scholar 

  • Kunisaki, Y. et al. Arteriolar niches maintain haematopoietic stem cell quiescence. Nature 502, 637–643 (2013).

    Article 
    ADS 
    PubMed 
    PubMed Central 
    CAS 

    Google Scholar 

  • Asada, N. et al. Differential cytokine contributions of perivascular haematopoietic stem cell niches. Nat. Cell Biol. 19, 214–223 (2017).

    Article 
    PubMed 
    PubMed Central 
    CAS 

    Google Scholar 

  • Pinho, S. et al. Lineage-biased hematopoietic stem cells are regulated by distinct niches. Dev. Cell 44, 634–641 (2018).

    Article 
    PubMed 
    PubMed Central 
    CAS 

    Google Scholar 

  • Niederkorn, J. Y. See no evil, hear no evil, do no evil: the lessons of immune privilege. Nat. Immunol. 7, 354–359 (2006).

    Article 
    PubMed 
    CAS 

    Google Scholar 

  • Fujisaki, J. et al. In vivo imaging of Treg cells providing immune privilege to the haematopoietic stem-cell niche. Nature 474, 216–219 (2011).

    Article 
    PubMed 
    PubMed Central 
    CAS 

    Google Scholar 

  • Hirata, Y. et al. CD150high bone marrow Tregs maintain hematopoietic stem cell quiescence and immune privilege via adenosine. Cell Stem Cell 22, 445–453 (2018).

    Article 
    PubMed 
    PubMed Central 
    CAS 

    Google Scholar 

  • Hirata, Y., Kakiuchi, M., Robson, S. C. & Fujisaki, J. CD150high CD4 T cells and CD150high regulatory T cells regulate hematopoietic stem cell quiescence via CD73. Haematologica 104, 1136–1142 (2019).

    Article 
    PubMed 
    PubMed Central 
    CAS 

    Google Scholar 

  • Hirata, Y. et al. MHC class I expression by donor hematopoietic stem cells is required to prevent NK cell attack in allogeneic, but not syngeneic recipient mice. PLoS ONE 10, e0141785 (2015).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Kakiuchi, M., Hirata, Y., Robson, S. C. & Fujisaki, J. Paradoxical regulation of allogeneic bone marrow engraftment and immune privilege by mesenchymal cells and adenosine. Transplant. Cell. Ther. 27, 92.e1–92 (2021).

    Article 
    PubMed 
    CAS 

    Google Scholar 

  • Kakiuchi, M., Hirata, Y., Robson, S. C. & Fujisaki, J. Transfer of stem cell niche-residential regulatory T cells prevents post-irradiation bone marrow injury. Haematologica 106, 891–893 (2021).

    Article 
    PubMed 

    Google Scholar 

  • Lu, D. & Kassab, G. S. Role of shear stress and stretch in vascular mechanobiology. J. R. Soc. Interface 8, 1379–1385 (2011).

    Article 
    PubMed 
    PubMed Central 
    CAS 

    Google Scholar 

  • Nogueira-Pedro, A. et al. Nitric oxide-induced murine hematopoietic stem cell fate involves multiple signaling proteins, gene expression, and redox modulation. Stem Cells 32, 2949–2960 (2014).

    Article 
    PubMed 
    CAS 

    Google Scholar 

  • Tiribuzi, R. et al. Nitric oxide depletion alters hematopoietic stem cell commitment toward immunogenic dendritic cells. Biochim. Biophys. Acta 1830, 2830–2838 (2013).

    Article 
    PubMed 
    CAS 

    Google Scholar 

  • Gur-Cohen, S. et al. PAR1 signaling regulates the retention and recruitment of EPCR-expressing bone marrow hematopoietic stem cells. Nat. Med. 21, 1307–1317 (2015).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Tjalkens, R. B., Carbone, D. L. & Wu, G. Detection of nitric oxide formation in primary neural cells and tissues. Methods Mol. Biol. 758, 267–277 (2011).

    Article 
    PubMed 
    PubMed Central 
    CAS 

    Google Scholar 

  • Lepiller, S. et al. Imaging of nitric oxide in a living vertebrate using a diamino-fluorescein probe. Free Radic. Biol. Med. 43, 619–627 (2007).

    Article 
    PubMed 
    CAS 

    Google Scholar 

  • Ngwa, C. & Liu, F. CD200–CD200R signaling and diseases: a potential therapeutic target? Int. J. Physiol. Pathophysiol. Pharmacol. 11, 297–309 (2019).

    PubMed 
    PubMed Central 
    CAS 

    Google Scholar 

  • Wang, Z. M., Gao, X. F., Zhang, J. J. & Chen, S. L. Primary cilia and atherosclerosis. Front. Physiol. 12, 640774 (2021).

    Article 
    ADS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Bangs, F. K., Schrode, N., Hadjantonakis, A. K. & Anderson, K. V. Lineage specificity of primary cilia in the mouse embryo. Nat. Cell Biol. 17, 113–122 (2015).

    Article 
    PubMed 
    PubMed Central 
    CAS 

    Google Scholar 

  • Trimm, E. & Red-Horse, K. Vascular endothelial cell development and diversity. Nat. Rev. Cardiol. 20, 197–210 (2023).

    Article 
    PubMed 

    Google Scholar 

  • Hooper, A. T. et al. Engraftment and reconstitution of hematopoiesis is dependent on VEGFR2-mediated regeneration of sinusoidal endothelial cells. Cell Stem Cell 4, 263–274 (2009).

    Article 
    PubMed 
    PubMed Central 
    CAS 

    Google Scholar 

  • Rafii, S., Butler, J. M. & Ding, B. S. Angiocrine functions of organ-specific endothelial cells. Nature 529, 316–325 (2016).

    Article 
    ADS 
    PubMed 
    PubMed Central 
    CAS 

    Google Scholar 

  • Kobayashi, H. et al. Angiocrine factors from Akt-activated endothelial cells balance self-renewal and differentiation of haematopoietic stem cells. Nat. Cell Biol. 12, 1046–1056 (2010).

    Article 
    PubMed 
    PubMed Central 
    CAS 

    Google Scholar 

  • Xu, C. et al. Stem cell factor is selectively secreted by arterial endothelial cells in bone marrow. Nat. Commun. 9, 2449 (2018).

    Article 
    ADS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Sawai, C. M. et al. Hematopoietic stem cells are the major source of multilineage hematopoiesis in adult animals. Immunity 45, 597–609 (2016).

    Article 
    PubMed 
    PubMed Central 
    CAS 

    Google Scholar 

  • Paulson, D. et al. Loss of primary cilia protein IFT20 dysregulates lymphatic vessel patterning in development and inflammation. Front. Cell Dev. Biol. 9, 672625 (2021).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Sharma, N. et al. Proximal tubule proliferation is insufficient to induce rapid cyst formation after cilia disruption. J. Am. Soc. Nephrol. 24, 456–464 (2013).

    Article 
    PubMed 
    PubMed Central 
    CAS 

    Google Scholar 

  • Dong, S. et al. Chaperone-mediated autophagy sustains haematopoietic stem-cell function. Nature 591, 117–123 (2021).

    Article 
    ADS 
    PubMed 
    PubMed Central 
    CAS 

    Google Scholar 

  • Casares-Crespo, L., Calatayud-Baselga, I., Garcia-Corzo, L. & Mira, H. On the role of basal autophagy in adult neural stem cells and neurogenesis. Front. Cell. Neurosci. 12, 339 (2018).

    Article 
    PubMed 
    PubMed Central 
    CAS 

    Google Scholar 

  • Chua, B. A. et al. Hematopoietic stem cells preferentially traffic misfolded proteins to aggresomes and depend on aggrephagy to maintain protein homeostasis. Cell Stem Cell 30, 460–472.e6 (2023).

    Article 
    PubMed 
    PubMed Central 
    CAS 

    Google Scholar 

  • Wink, D. A. et al. Mechanisms of the antioxidant effects of nitric oxide. Antioxid. Redox Signal. 3, 203–213 (2001).

    Article 
    PubMed 
    CAS 

    Google Scholar 

  • Aref, S., Azmy, E. & El-Gilany, A. H. Upregulation of CD200 is associated with regulatory T cell expansion and disease progression in multiple myeloma. Hematol. Oncol. 35, 51–57 (2017).

    Article 
    PubMed 
    CAS 

    Google Scholar 

  • Yamamoto, R. et al. Large-scale clonal analysis resolves aging of the mouse hematopoietic stem cell compartment. Cell Stem Cell 22, 600–607 (2018).

    Article 
    PubMed 
    PubMed Central 
    CAS 

    Google Scholar 

  • Khan, I. Z. et al. The CD200–CD200R axis promotes squamous cell carcinoma metastasis via regulation of cathepsin K. Cancer Res. 81, 5021–5032 (2021).

    Article 
    PubMed 
    PubMed Central 
    CAS 

    Google Scholar 

  • Kalyanaraman, H. et al. Nongenomic thyroid hormone signaling occurs through a plasma membrane-localized receptor. Sci. Signal. 7, ra48 (2014).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Komatsu, M. et al. Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice. J. Cell Biol. 169, 425–434 (2005).

    Article 
    PubMed 
    PubMed Central 
    CAS 

    Google Scholar 

  • Ehling, M., Adams, S., Benedito, R. & Adams, R. H. Notch controls retinal blood vessel maturation and quiescence. Development 140, 3051–3061 (2013).

    Article 
    PubMed 
    CAS 

    Google Scholar 

  • Ito, H., Kurtz, J., Shaffer, J. & Sykes, M. CD4 T cell-mediated alloresistance to fully MHC-mismatched allogeneic bone marrow engraftment is dependent on CD40–CD40 ligand interactions, and lasting T cell tolerance is induced by bone marrow transplantation with initial blockade of this pathway. J. Immunol. 166, 2970–2981 (2001).

    Article 
    PubMed 
    CAS 

    Google Scholar 

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