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A bile acid could explain how calorie restriction slows ageing

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Nature, Published online: 18 December 2024; doi:10.1038/d41586-024-04062-1

Could lithocholic acid, a compound produced when gut bacteria process bile, be the missing link between a low-calorie diet and its age-defying effects? Experiments in mice, flies and nematode worms provide clues.

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